High-resolution MRI of uveal melanoma using a microcoil phased array at 7 T

Autor: J W M, Beenakker, G A, van Rijn, G P M, Luyten, A G, Webb
Rok vydání: 2013
Předmět:
Zdroj: NMR in biomedicine. 26(12)
ISSN: 1099-1492
Popis: High-field MRI is a promising technique for the characterisation of ocular tumours, both in vivo and after enucleation. For in vivo imaging at 7 T, a dedicated three-element microcoil array was constructed as a high-sensitivity receive-only device. Using a dedicated blink/fixation protocol, high-resolution in vivo images could be acquired within 3 min in volunteers and patients with no requirement for post-acquisition image registration. Quantitative measures of axial length, aqueous depth and lens thickness in a healthy volunteer were found to agree well with standard ocular biometric techniques. In a patient with uveal melanoma, in vivo MRI gave excellent tumour/aqueous body contrast. Ex vivo imaging of the enucleated eye showed significant heterogeneity within the tumour.
Databáze: OpenAIRE