[The isolation and characteristics of reassortants between the Lassa and Mopeia arenaviruses]

Autor:	I S, Lukashevich, A D, Vasiuchkov, T A, Stel'makh, E P, Scheslenok, A G, Shabanov
Rok vydání:	1991
Předmět:	Recombination Genetic Phenotype Virus Cultivation Genotype Animals Nucleic Acid Hybridization RNA Viral DNA Viral Plaque Assay Arenaviridae DNA Probes Lassa virus Vero Cells
Zdroj:	Voprosy virusologii. 36(2)
ISSN:	0507-4088
Popis:	Reassortants with a mixed phenotype were produced by combined inoculation of Vero cells with Lassa and Mopeya viruses. These reassortants produced small plaques (Mopeya virus phenotype) and were not pathogenic for newborn mice (Lassa virus phenotype). The genotype of the reassortants was studied by dot hybridization experiments on filters using cDNA-probes differentiating genome segments of these viruses. The reassortants were shown to have Mopeya virus L-RNA and Lassa virus S-RNA.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::e725d81126054bb95c01c37e0c6c5bf3 https://pubmed.ncbi.nlm.nih.gov/1882522 Zobrazit plný text záznamu