[Solid phase synthesis and chromatographic characteristics of nucleophilic agents conjugated with oligonucleotides containing 5'-terminal carboxyl group]

Autor: A V, Kachalova, V N, Tashlitskiĭ, D A, Stetsenko, E A, Romanova, M J, Gait, T S, Oretskaia
Rok vydání: 2003
Předmět:
Zdroj: Bioorganicheskaia khimiia. 29(3)
ISSN: 0132-3423
Popis: Conjugates of amines or short peptides with oligonucleotides containing 5'-terminal carboxyl group were prepared by solid phase chemical synthesis. A correlation between the physicochemical parameters and retention times of the synthesized conjugates was established by ion-pair reversed-phase HPLC.
Databáze: OpenAIRE