A micromodification of the CH50 test for the classical pathway of complement

Autor:	T J, Fetterhoff, R C, McCarthy
Rok vydání:	1984
Předmět:	Erythrocytes Sheep Antibody Formation Methods Animals Humans Complement Pathway Classical Complement System Proteins Complement Activation Hemolysis
Zdroj:	Journal of clinicallaboratory immunology. 14(4)
ISSN:	0141-2760
Popis:	A micromodification of the CH50 assay of Kabat and Mayer is described in which the total reaction volume has been reduced five-fold. This assay utilizes sheep red blood cells pooled from multiple animals rather than from a single animal to avoid screening procedures of red blood cells from individual sheep. Analysis of natural hemolysin activity in normal serum revealed a correlation with elevated CH50 titers. However, this correlation does not appear to effect the clinical interpretation of the results.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::e42359e15cb921d782716cbaa450c0d2 https://pubmed.ncbi.nlm.nih.gov/6492124 Zobrazit plný text záznamu