| Autor: |
E W, Richards, M, Abu Khaled, C L, Watkins, C L, Long |
| Rok vydání: |
1991 |
| Předmět: |
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| Zdroj: |
Nutrition (Burbank, Los Angeles County, Calif.). 7(5) |
| ISSN: |
0899-9007 |
| Popis: |
Nuclear magnetic resonance (NMR) spectroscopy has been reported as an alternative method for quantitating deuterium oxide concentrations in the evaluation of total-body-water in humans. However, the presence of dissolved plasma proteins results in an underestimation of deuterium NMR (2H-NMR) intensity ratios, thereby causing an overestimation (5-6%) of total-body-water (TBW) values determined from nonsublimed patient plasma samples. We demonstrate that plasma samples must be corrected for the volume percentage of water in plasma. Correction of initial 2H-NMR intensity ratios with a factor of 0.93 results in intensity ratios comparable to those determined from plasma samples subjected to vacuum sublimation to remove all plasma solutes. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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