| Autor: |
Stefanie, Quach, Adrien, Holzgreve, Lena, Kaiser, Marcus, Unterrainer, Franziska J, Dekorsy, Debie V, Nelwan, Laura M, Bartos, Sabrina V, Kirchleitner, Jonathan, Weller, Lorraine, Weidner, Maximilian, Niyazi, Viktoria C, Ruf, Jochen, Herms, Sophia, Stöcklein, Christian, Wetzel, Markus J, Riemenschneider, Louisa, V Baumgarten, Niklas, Thon, Matthias, Brendel, Rainer, Rupprecht, Peter, Bartenstein, Joerg-Christian, Tonn, Nathalie L, Albert |
| Rok vydání: |
2022 |
| Zdroj: |
European journal of nuclear medicine and molecular imaging. |
| ISSN: |
1619-7089 |
| Popis: |
Glioma patients, especially recurrent glioma, suffer from a poor prognosis. While advances to classify glioma on a molecular level improved prognostication at initial diagnosis, markers to prognosticate survival in the recurrent situation are still needed. As 18 kDa translocator protein (TSPO) was previously reported to be associated with aggressive histopathological glioma features, we correlated the TSPO positron emission tomography (PET) signal using [In patients with [Eighty-eight consecutive patients were evaluated. TSPO tracer uptake correlated with tumor grade at recurrence (p 0.05), with no significant differences in IDH-wild-type versus IDH-mutant tumors. Within the subgroup of IDH-mutant glioma (n = 46), patients with low SUVOur data suggest that TSPO PET using [ |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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