Cerebral venous volume changes and pressure autoregulation in critically ill infants

Autor:	Vedavalli, Govindan, Rathinaswamy, Govindan, An N, Massaro, Tareq, Al-Shargabi, Nickie N, Andescavage, Gilbert, Vezina, Jonathan, Murnick, Yunfei, Wang, Marina, Metzler, Caitlin, Cristante, Christopher, Swisher, Daniel, Reich, Adre du, Plessis
Rok vydání:	2019
Předmět:	Cerebrovascular Circulation Critical Illness Infant Newborn Homeostasis Humans Infant Blood Pressure Prospective Studies Infant Premature
Zdroj:	Journal of perinatology : official journal of the California Perinatal Association. 40(5)
ISSN:	1476-5543
Popis:	To determine whether ventilator-related fluctuations in cerebral blood volume (CBV) are associated with cerebral pressure passivity.In a prospective study of newborns undergoing positive-pressure ventilation, we calculated coherence between continuous mean arterial pressure (MAP) and cerebral near-infrared spectroscopy hemoglobin difference (HbD). Significant HbD-MAP coherence indicated cerebral pressure passivity. CBV changes were measured as the spectral power of total hemoglobin (SWe studied 68 subjects with prematurity (n = 19), congenital heart disease (n = 11), and hypoxic-ischemic encephalopathy (n = 38). SIn sick newborns, ventilator-related CBV fluctuations may predispose to cerebral pressure passivity, which may predispose to an adverse neonatal outcome.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::dfa0836b2f5d829c838b4d5c707df7b2 https://pubmed.ncbi.nlm.nih.gov/32157218 Zobrazit plný text záznamu Full text from SpringerLink