[On cytocidic effect of exogenous modified DNA]

Autor: A N, Shutko, N N, Shatinina, L P, Ekimova
Rok vydání: 1978
Předmět:
Zdroj: Ukrainskii biokhimicheskii zhurnal (1. 50(5)
ISSN: 0201-8470
Popis: The number of defects of the secondary structure and dispersions of the molecular weights of DNA preparations were studied before and after their gamma-irradiation within a 5-2500 krad range of doses. These results are compared with the ability of the irradiated preparations to induce death of thymocytes irradiated in vivo during their combined incubation in vitro. It is established that the DNA biological activity is a result of the presence in the total preparation of molecule fractions of 5.10(6) or 1.10(6) Daltons with 3 or 50-80 defects of the secondary structure.
Databáze: OpenAIRE