Humanization and directed evolution of the selenium-containing

Autor: Yan, Xu, Pengju, Li, Jiaojiao, Nie, Qi, Zhao, Shanshan, Guan, Ziyu, Kuai, Yongbo, Qiao, Xiaoyu, Jiang, Ying, Li, Wei, Li, Yuhua, Shi, Wei, Kong, Yaming, Shan
Rok vydání: 2018
Zdroj: RSC advances. 8(31)
ISSN: 2046-2069
Popis: According to the binding site structure and the catalytic mechanism of the native glutathione peroxidase (GPX), three glutathione derivatives, GSH-S-DNP butyl ester (hapten Be), GSH-S-DNP hexyl ester (hapten He) and GSH-S-DNP hexamethylene ester (hapten Hme) were synthesized. By a four-round panning with a human synthetic
Databáze: OpenAIRE