Labial salivary gland biopsy for diagnosis of amyloid polyneuropathy

Autor:	E, Lechapt-Zalcman, F J, Authier, A, Creange, M C, Voisin, R K, Gherardi
Rok vydání:	1999
Předmět:	Amyloid Predictive Value of Tests Biopsy Humans Peripheral Nervous System Diseases Peroneal Nerve Middle Aged Amyloid Neuropathies Salivary Glands Minor Immunohistochemistry Sensitivity and Specificity Lip
Zdroj:	Musclenerve. 22(1)
ISSN:	0148-639X
Popis:	Biopsies of peroneal nerve and labial salivary gland (LSG) were performed in 32 patients with polyneuropathy of unknown origin. Amyloid deposits were detected in 7 LSG (transthyretin=5; amyloid, light chain derived=2) and 6 nerve biopsies. Familial amyloid and light chain amyloid polyneuropathies were subsequently confirmed by relevant tests. We propose that LSG biopsy, a minimally invasive test that may document both sicca syndrome and amyloidosis, should be systematically performed in the investigation of patients with axonal polyneuropathies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::d1c102169077ec7862c80ec68f5378f0 https://pubmed.ncbi.nlm.nih.gov/9883863 Zobrazit plný text záznamu Plný text