[Quantitative patterns of tubocurarine action on the synaptic potentials of frog muscle]

Autor: V M, Grigor'ev, A F, Danilov, A I, Skliarov
Rok vydání: 1988
Předmět:
Zdroj: Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. 74(9)
ISSN: 0015-329X
Popis: The dependence of amplitude of synaptic potentials (EPP and mEPP) upon the d-tubocurarine concentration was studied in the frog cutaneous pectoral muscle. In the presence of d-tubocurarine up to 5 x 10(-7) M, the amplitude of EPP and mEPP decreased to the extent which strictly followed competitive action of d-tubocurarine. At a higher concentration, the inhibition of synaptic potentials was stronger than would be expected assuming that d-tubocurarine can only act as a competitive antagonist.
Databáze: OpenAIRE