Relationship of energy metabolism detected by 31P-MRS in the human brain with mental fatigue

Autor: T, Kato, J, Murashita, T, Shioiri, T, Inubushi, N, Kato
Rok vydání: 1999
Předmět:
Zdroj: Neuropsychobiology. 39(4)
ISSN: 0302-282X
Popis: To search for a possible relationship between brain energy metabolism and mental fatiguability, 10 normal volunteers were examined by 31P-MRS (phosphorus-31 magnetic resonance spectroscopy) in the occipital cortex during photic stimulation (PS), and Uchida-Kraepelin test (UKT), a standardized serial calculation task, was used for measurement of intraindividual characteristics of mental fatigue in these subjects. More decrease of phosphocreatine measured by 31P-MRS during the PS was significantly associated with more effects of rest assessed by UKT (r = -0.86, p0.005). More decrease in pH after PS was associated with steeper decline of performance (r = 0.78, p0.01). These findings suggest that characteristics of brain energy metabolism in an individual may relate to intrinsic patterns of mental fatigability.
Databáze: OpenAIRE