| Autor: |
Liang, Gao, Xin-Zhu, Lin, Qian-Qian, Wu, Yu-Cong, Lin, Kun-Yao, Hong |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Zhongguo Dang Dai Er Ke Za Zhi |
| ISSN: |
1008-8830 |
| Popis: |
OBJECTIVE: To study the correlation between coagulation function and gestational age in preterm infants and the possible value of coagulation function measurement in predicting hemorrhagic diseases. METHODS: The clinical data of preterm infants who were hospitalized between September 2016 and August 2017 were collected. The coagulation indicators were measured within 2 hours after birth. According to the gestational age, the preterm infants were divided into late preterm infant group (n=322), early preterm infant group (n=241) and extremely/very early preterm infant group (n=128). Coagulation function was compared among the three groups, as well as between the preterm infants with and without hemorrhagic diseases within 3 days after birth. RESULTS: There were significant differences in thrombin time (TT), prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen degradation product (FDP) and D-dimer (DD) among the three groups (P < 0.05). APTT, PT, FDP and DD were negatively correlated with gestational age, while TT was positively correlated with gestational age (P < 0.05). The preterm infants with hemorrhagic diseases had a longer APTT and a higher level of DD (P < 0.05). CONCLUSIONS: Coagulation function gradually becomes mature in preterm infants with the increase in gestational age. Abnormal APTT and DD indicate that preterm infants may have a higher risk of hemorrhagic diseases. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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