[Severe hyponatraemia and central pontine myelinolysis: be careful with other factors!]

Autor: S, Ruiz, M, Alzieu, L, Niquet, S, Vergne, D, Lathuile, J, Campistron
Jazyk: francouzština
Rok vydání: 2008
Předmět:
Zdroj: Annales francaises d'anesthesie et de reanimation. 28(1)
ISSN: 1769-6623
Popis: Central pontine myelinolysis covers very different clinical aspects, ranging from discrete tremor to quadriplegia. Rapid correction of hyponatraemia is a well-known risk factor, particularly in chronic alcohol abusers. We describe the case of a 46-year-old chronic alcoholic, suffering from denutrition. He developed a quadriplegia and a facial diplegia two weeks after a slow correction of a chronic hyponatraemia associated with hypokalaemia. Central pontine myelinolysis was formally diagnosed by MRI findings. In our case, the correction of hyponatraemia is not the only causal agent of this syndrome; hypokalaemia and denutrition seem to be predisposing factors too. For these reasons, glial cells are more vulnerable to osmotic variations. Despite of severe initial symptoms, the evolution was favourable with a quasi complete recovery.
Databáze: OpenAIRE