Clinical inquiries. What is the best management for patients who have a TIA while on aspirin therapy?

Autor:	Nabila, Ahmed, John B, Coffey, Robert, Oh
Rok vydání:	2006
Předmět:	Stroke Evidence-Based Medicine Aspirin Ischemic Attack Transient Risk Factors Humans Drug Therapy Combination Platelet Aggregation Inhibitors Randomized Controlled Trials as Topic
Zdroj:	The Journal of family practice. 55(7)
ISSN:	0094-3509
Popis:	Alternative antiplatelet therapy for stroke prevention is indicated for patients who experience transient ischemic attacks (TIAs) while on aspirin therapy (strength of recommendation [SOR]: A, based on 1 meta-analysis and 1 randomized controlled trial). The combination of aspirin and extended-release dipyridamole reduces the risk of stroke following a TIA (SOR: A). Thieno-pyridines (eg, clopidogrel and ticlopidine) are an alternative for patients at high risk for a cardioembolic event. Ticlopidine reduces the risk of stroke following TIA, specifically showing benefit for patients previously on aspirin (SOR: A). Clopidogrel has not shown significant reduction in reoccurrence of stroke and has not been studied for patients with a previous TIA. Aspirin and a thieno-pyridine do not provide significant additional reduction in secondary strokes (SOR: A).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::c1f10cb5596c1af03f6a1269ff68667b https://pubmed.ncbi.nlm.nih.gov/16822451 Zobrazit plný text záznamu