[Effectiveness of oxytetracycline and chingamin on cold injury in rats]

Autor: N N, Aleutskiĭ, O V, Buiuklinskaia, E A, Malykh, N A, Nazarenko
Rok vydání: 1995
Předmět:
Zdroj: Patologicheskaia fiziologiia i eksperimental'naia terapiia. (2)
ISSN: 0031-2991
Popis: The preventive and therapeutical effects of oxytetracycline hydrochloride, 10 mg/kg b.w., and chingamine, 50 mg/kg b.w., were studied in frostbites caused by ethyl chloride. The experiments were conducted on adult albino Wistar rats. The two drugs given orally twice a day for 15 days or more prevented the development of frost bite; clinical, biochemical, and histological parameters becoming normal. Chingamine was found to be more effective, which makes it promising for further experimental and clinical studies.
Databáze: OpenAIRE