Relationship of Height to Site‐Specific Fracture Risk in Postmenopausal Women

Autor: Armstrong, Miranda EG, Kirichek, Oksana, Cairns, Benjamin J, Green, Jane, Reeves, Gillian K
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Bone and Mineral Research
ISSN: 1523-4681
0884-0431
Popis: Height has been associated with increased risk of fracture of the neck of femur. However, information on the association of height with fractures at other sites is limited and conflicting. A total of 796,081 postmenopausal women, who reported on health and lifestyle factors including a history of previous fractures and osteoporosis, were followed for 8 years for incident fracture at various sites by record linkage to National Health Service hospital admission data. Adjusted relative risks of fracture at different sites per 10‐cm increase in height were estimated using Cox regression. Numbers with site‐specific fractures were: humerus (3036 cases), radius and/or ulna (1775), wrist (9684), neck of femur (5734), femur (not neck) (713), patella (649), tibia and/or fibula (1811), ankle (5523), and clavicle/spine/rib (2174). The risk of fracture of the neck of femur increased with increasing height (relative risk [RR] = 1.48 per 10‐cm increase, 99% confidence interval [CI] 1.39–1.57) and the proportional increase in risk was significantly greater than for all other fracture sites (p heterogeneity
Databáze: OpenAIRE
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