Analysis of CX3CR1 haplodeficiency in male and female APP

Autor:	Anne-Laure, Hemonnot-Girard, Audrey J, Valverde, Jennifer, Hua, Charlene, Delaygue, Nathalie, Linck, Tangui, Maurice, François, Rassendren, Helene, Hirbec
Rok vydání:	2020
Předmět:	Male Amyloid beta-Peptides CX3C Chemokine Receptor 1 Brain Mice Transgenic Plaque Amyloid Amyloid beta-Protein Precursor Disease Models Animal Mice Alzheimer Disease Disease Progression Animals Female Microglia
Zdroj:	Brain, behavior, and immunity. 91
ISSN:	1090-2139
Popis:	Microglia, the resident immune cells of the brain, have recently emerged as key players in Alzheimer Disease (AD) pathogenesis, but their roles in AD remain largely elusive and require further investigation. Microglia functions are readily altered when isolated from their brain environment, and microglia reporter mice thus represent valuable tools to study the contribution of these cells to neurodegenerative diseases such as AD. The CX3CR1
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::bb25a8b3ecb1f78508ee5704b6c033e2 https://pubmed.ncbi.nlm.nih.gov/33190798 Zobrazit plný text záznamu Full Text from ScienceDirect