Vaginal discharge: aetiological agents and evaluation of syndromic management in Lagos
| Autor: | C L, Onyekonwu, Y M, Olumide, F A, Oresanya, G C, Onyekonwu |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Nystatin Adolescent Disease Management Nigeria Vaginosis Bacterial Middle Aged Sensitivity and Specificity Uterine Cervicitis Young Adult Age Distribution Treatment Outcome Vaginal Discharge Anti-Infective Agents Socioeconomic Factors Prevalence Humans Female Trichomonas Vaginitis Physical Examination Algorithms Candidiasis Vulvovaginal |
| Zdroj: | Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria. 20(1) |
| ISSN: | 1115-2613 |
| Popis: | The WHO introduced the syndromic management to help in the control of STIs in resource-poor settings. This needs to be adapted to local settings taking into consideration the prevalence of the various organisms causing STIs. This has given rise to a need to validate the algorithm. The study aimed to correlate the syndromic management treatment algorithm for vaginal discharge with the aetiological diagnosis based on laboratory investigations. Specifically, the sensitivity, specificity and positive predictive values of the syndromic management against a gold standard laboratory diagnosis were evaluated.A total of 195 consecutive patients presenting to the study sites with vaginal discharge were enrolled in the study. Information on sociodemographic data was obtained with the aid of questionnaires. Samples were taken and examined for candida, trichomonas, bacterial vaginosis (BV), chlamydia and gonorrheal infections, after speculum and vaginal examinations.The sensitivity and positive predictive values (PPV) of the syndromic management in detecting vaginal infections performed better than corresponding values for cervicitis. The algorithm for cervicitis improved on addition of speculum examination (36% and 32.1% for sensitivity and PPV respectively).The study shows that the syndromic diagnosis for vaginal discharge fares better for vaginitis, especially with addition of speculum examination. The application of syndromic diagnosis for cervicitis resulted in omission of patients who had evidence of cervical infections by bacteriologic examination. |
| Databáze: | OpenAIRE |
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