[Effect of the nucleic acids from the ascitic fluid of Ehrlich's tumor on its transplantability]

Autor:	A S, Belokhvostov, N K, Grikurova
Rok vydání:	1981
Předmět:	Cytotoxicity Immunologic Male Mice Inbred C57BL Mice Mice Inbred C3H Liver Neoplasms Experimental Nucleic Acids Animals Ascitic Fluid Lymphocytes In Vitro Techniques Carcinoma Ehrlich Tumor Neoplasm Transplantation
Zdroj:	Voprosy onkologii. 27(12)
ISSN:	0507-3758
Popis:	The effect of nucleic acids isolated from ascitic fluid of Ehrlich tumor and Zaidela's hepatoma on the survival rate of C3Ha mice inoculated with Ehrlich tumor cells was studied. While nucleic acid preparations suppressed the cytotoxicity of immune lymphocytes in vitro, they failed to increase frequency of tumor inoculation in vivo. The addition of nucleic acid preparation to tumor cells mixed with syngeneic lymphocytes did not block immune defense against tumor growth either. The differences in the effects of nucleic acid preparations in vivo and in vitro are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::b97c4b5af3727691aef0c9229896f081 https://pubmed.ncbi.nlm.nih.gov/7324403 Zobrazit plný text záznamu