| Autor: |
Fatemeh, Mehdizadeh Sari, Shiva, Mirkalantari, Shohreh, Nikoo, Fatemeh, Sepahvand, Leila, Allahqoli, Arezoo, Asadi, Malihe, Talebi |
| Rok vydání: |
2022 |
| Zdroj: |
Iranian journal of microbiology. 14(5) |
| ISSN: |
2008-3289 |
| Popis: |
Endometriosis is defined as the presence of endometrial tissue outside the uterine cavity. Peripheral blood monocytes cells (PBMCs) may have altered function to some extent in women with endometriosis.In this study, peripheral blood samples were obtained from endometriosis patients (n=11) and non-endometriosis individuals (n=11). After isolation of peripheral blood mononuclear cells with Ficoll, cells were cultured in the presence and absence of phytohemagglutinin. Also, these cells were co-cultured with 1×10The results showed that in endometriosis patients, the production of pro-inflammatory cytokines, including IL-1 and IL-6, by PBMC was increased compared to non-endometriosis subjects, and stimuli such as PHA intensified this elevation. Also,According to the results of the current study, IL-1 and IL-6 production was significantly increased in PMBCs of endometriosis patients compared to that of the healthy controls. Also |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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