| Autor: |
Helen, Whitford, Christina E, Kure, Aimee, Henriksen, Jamie, Hobson, Greg I, Snell, Bronwyn J, Levvey, Silvana F, Marasco, Julian H, Gooi, Adam, Zimmet, Justin, Negri, Adrian, Pick, Mark, Buckland, Trevor, Williams, Glenn, Westall, Miranda A, Paraskeva, Catherine, Martin, David C, McGiffin |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 39(1) |
| ISSN: |
1557-3117 |
| Popis: |
A donor arterial POIn 93 brain dead lung donors, arterial blood gases were drawn in the intensive care unit (ICU) just before procurement and each of the 4 donor pulmonary veins in the operating room (OR). No donor lungs were rejected for transplantation based on the last ICU or OR P/F ratio, and EVLP was not used. The recipients were followed up 6 and 12 months following transplantation.There were 93 recipients of bilateral lung transplantation. An arterial P/F ratio of300 was largely driven by a low P/F ratio in the lower lobes. There were no differences between the recipients receiving donor lungs where the ICU P/F ratio was300 compared with ≥ 300 in the time to extubation, grade of primary graft dysfunction, pulmonary function at 6 and 12 months, and 12-month survival.From this study:(1) If a donor P/F threshold of 300 was adhered to, 36% would have been rejected, and (2) The donor P/F ratio threshold of 300 is excessively conservative and results in the wastage of donor lungs and the application of unnecessary EVLP. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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