[Impact of an active surveillance program and infection control measures on the incidence of carbapenem-resistant gram-negative bacilli in an intensive care unit]

Autor: Juan Martín, Vargas, María Paula, Moreno Mochi, Carolina Graciela, López, Janet Alejandra, Alarcón, Nancy, Acosta, Karina, Soria, Juan Manuel, Nuñez, Sandra, Villafañe, Jorge, Ramacciotti, Rosa, Del Campo, María Angela, Jure
Rok vydání: 2020
Předmět:
Zdroj: Revista Argentina de microbiologia. 54(2)
ISSN: 0325-7541
Popis: Hospital-acquired infections caused by carbapenem-resistant Gram-negative bacteria (CRGNB) have been increasingly reported worldwide and are associated with high rates of mortality especially in intensive care units(ICUs). Early identification through rectal surveillance cultures and implementation of infection control measures(ICM) including contact precautions, staff education on cleaning and hand hygiene may reduce the spread of these microorganisms. The aim of this work was to assess the impact of enhanced ICM on CRGNB colonization and to describe the molecular epidemiology of these bacteria in a polyvalent ICU in a tertiary level hospital. A prospective study including audits and active surveillance culture program, with molecular characterization, was conducted before and after the implementation of prevention programs and infection control measures. Microbiological screening was performed in chromogenic media; PCR targeting β-lactamases genes (bla
Databáze: OpenAIRE