Development and selection of T cells: how many subsets? How many rules?

Autor: Paweł, Kisielow
Rok vydání: 2003
Předmět:
Zdroj: Archivum immunologiae et therapiae experimentalis. 51(6)
ISSN: 0004-069X
Popis: Since the discovery indicating that thymus-derived lymphocytes (T cells) can be divided into two subpopulations: CD8+ (killer) and CD4+ (helper) cells, subsequent studies revealed a bewildering heterogeneity of T cells. In the present review an attempt is made to present the current picture of T cell heterogeneity, introduce some order into the nomenclature, and summarize the rules behind the development and selection of different currently recognized T cell subsets.
Databáze: OpenAIRE