| Autor: |
Gustavo, Pierdominici-Sottile, Vanesa, Racigh, Agustín, Ormazábal, Juliana, Palma |
| Rok vydání: |
2019 |
| Zdroj: |
The journal of physical chemistry. B. 123(5) |
| ISSN: |
1520-5207 |
| Popis: |
P2X receptors are a group of trimeric cationic channels that are activated by adenosine 5'-triphosphate. They perform critical roles in the membranes of mammalian cells, and their improper functioning is associated with numerous diseases. Despite the vast amount of research devoted to them, several aspects of their operation are currently unclear, including the causes of their charge selectivity. We present the results of molecular dynamics simulation, which shed light on this issue for the case of P2X |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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