[Results of a randomized, double blind prospective study of intravesical chemoprophylaxis with 2 drugs: adriamycin and mitomycin; and 2 ways of initiating the instillations: early and late. Effect on recurrence and progression]

Autor:	I, Iborra Juan, J V, Ricos Torrent, J L, Monrós Lliso, R, Dumont Martínez, J, Casanova Ramón-Borja, E, Solsona Narbón
Rok vydání:	1992
Předmět:	Male Carcinoma Transitional Cell Time Factors Middle Aged Combined Modality Therapy Drug Administration Schedule Mitomycins Administration Intravesical Double-Blind Method Urinary Bladder Neoplasms Doxorubicin Humans Female Prospective Studies Neoplasm Recurrence Local Follow-Up Studies
Zdroj:	Archivos espanoles de urologia. 45(10)
ISSN:	0004-0614
Popis:	The results of a double blind prospective study comparing the chemoprophylactic effects of adriamycin and mitomycin C and two modes of instillation (early: 6 hours following transurethral resection; late: 7-14 days later) for superficial carcinoma of the bladder are presented herein. Since the minimum follow up is over 5 years, the effects on tumor progression and mortality achieved by each of the 4 arms of the protocol were also evaluated. Concerning tumor recurrence, early instillation of mitomycin and overall early instillation therapy achieved significantly better results (p0.01). No differences, however, were observed relative to tumor progression or mortality.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::aea0885fcc92943716067abdf8d1e9bc https://pubmed.ncbi.nlm.nih.gov/1294028 Zobrazit plný text záznamu