Cyba and Nox2 mutant rats show different incidences of eosinophilia in the genetic background- and sex-dependent manner

Autor: Masayuki, Mori, Jian, Dai, Hiroki, Miyahara, Ying, Li, Xiaojing, Kang, Kazuto, Yoshimi, Tomoji, Mashimo, Keiichi, Higuchi, Kiyoshi, Matsumoto
Rok vydání: 2022
Zdroj: Experimental animals.
ISSN: 1881-7122
Popis: The Matsumoto Eosinophilia Shinshu (MES) is a rat model for hereditary blood eosinophilia. The incidence of eosinophilia is 100% in both female and male MES. The primary cause of the eosinophilia in MES is a loss-of-function mutation in the gene encoding the cytochrome b-245, alpha polypeptide (Cyba
Databáze: OpenAIRE