[Perimembranous glomerulonephritis after treatment with D-penicillamine. Report on 31 cases (author's transl)]

Autor: H V, Gärtner, G H, Neild, A, Bohle, W, Hallauer, G, Hoppe-Seyler, F M, Lüttgen, P, Schollmeyer
Jazyk: němčina
Rok vydání: 1975
Předmět:
Zdroj: Klinische Wochenschrift. 53(17)
ISSN: 0023-2173
Popis: This report includes 31 patients who developed a perimembranous glomerulonephritis generally 7 months after the onset of the treatment of various illnesses with D-Penicillamine. In all cases the patients had a proteinuria, associated with a hematuria in 12 cases. After the treatment was stopped 8 patients rapidly developed a nephrotic syndrome, while its onset was more gradual in 12 other patients. 5 patients initially with a nephrotic syndrome had no proteinuria at the time of a second biopsy made up to 12 months later. In these 5 cases the typical changes of perimembranous glomerulonephritis observed on electron microscopy were much reduced in the second biopsy.
Databáze: OpenAIRE