[The phenotypic characteristics of healthy carriers of the antigenic structures of the influenza A virus]

Autor: L M, Tsybalova, A A, Sominina, T L, Popova, I E, Filippova, E A, Zibina, T A, Bekhtereva, I I, Konovalova, E M, Voĭtsekhovskaia, I B, Semilutskaia
Rok vydání: 1996
Předmět:
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii. (2)
ISSN: 0372-9311
Popis: Highly sensitive methods for the detection of viral antigens with the use of monoclonal or polyclonal enzyme immunoassay test systems, as well as virus-specific nucleic sequences (NS-gene) in polymerase chain reaction, made it possible to establish the fact of long-term asymptomatic virus carriership (AVC) in some of adolescent schoolchildren in a closed group. The occurrence of AVC varied at different phases of the epidemic process. The tendency to AVC was observed in individuals having blood group B (III) and HLA-A9 antigen of the major histocompatibility complex. The development of AVC occurred in the presence of a decreased level of humoral immunity. AVC was mainly registered among individuals, relatively resistant to relapsing clinically pronounced forms of respiratory virus infections.
Databáze: OpenAIRE