Deletion 20q in association with Philadelphia chromosome positive acute lymphoblastic leukemia. A report of two cases

Autor:	P E, Hollings, S M, Benjes, I, Rosman, P H, Fitzgerald
Rok vydání:	1995
Předmět:	Adult Male Adolescent Karyotyping Chromosomes Human Pair 20 Chromosome Mapping Humans Chromosome Deletion Precursor Cell Lymphoblastic Leukemia-Lymphoma
Zdroj:	Cancer genetics and cytogenetics. 79(1)
ISSN:	0165-4608
Popis:	Cytogenetic deletions involving the long arm of chromosome 20 are thought to be characteristic of myeloid disorders. We report clinical and cytogenetic observations of two adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia: one with a smaller 20q deletion that was the sole cytogenetic abnormality in a persisting remission clone, the other with a larger 20q deletion that was a late addition to the leukemic clone at disease relapse following allogeneic bone marrow transplantation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::a584a4d9154d89709edee57ecf7fc931 https://pubmed.ncbi.nlm.nih.gov/7850748 Zobrazit plný text záznamu Full Text from ScienceDirect