[The possibilities for enhancing the immunogenicity of adenovirus hexon]

Autor: L A, Tarasishin, N S, Diachenko, A V, Nekrasov, S V, Lel'chuk, T M, Andronova
Rok vydání: 1990
Předmět:
Zdroj: Mikrobiologicheskii zhurnal. 52(3)
ISSN: 0201-8462
Popis: Synthetic polyelectrolytes and muramyldipeptide derivatives are tested as immunostimulators. It is established that the level of antibody-forming cells and specific (virus-neutralizing and precipitating) antibodies considerably rises during the immunization of human adenovirus I hexon in the combination with N-acetylglucosaminyl-muramyldipeptide and conjugation with a copolymer including acrylic acid and N-vinylpyrrolidone. A more expressed intensification of the antibody-formation is observed with the use of polyelectrolytes.
Databáze: OpenAIRE