| Autor: |
Tadafumi, Fukata, Yoshiro, Ito, Hiromichi, Miyagaki, Hisashi, Nishida, Yasuhiro, Toyoda, Tatsushi, Shingai, Osamu, Takayama, Setsuko, Yoshioka, Shigeyuki, Hojo, Takayuki, Fukuzaki, Hiroaki, Ohigashi |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Gan to kagaku ryoho. Cancerchemotherapy. 46(4) |
| ISSN: |
0385-0684 |
| Popis: |
A 78-year-old woman had a semicircular ulcerative lesion of AV 7 cm, as detected using colonoscopy, and pathologic examination based on a biopsy showed well-differentiated adenocarcinoma. On contrast-enhanced CT of the liver, a number of nodular lesions that seemed to be liver metastases were observed. It was decided to administer chemotherapy containing mFOLFOX6 plus panitumumab. Bilateral hemorrhage of the ocular conjunctiva and eyelid edema were observed from the 4th day of chemotherapy. Edema of the lips, epidermolysis, and erythema appeared in addition to vision impairment. We diagnosed her with SJS based on these symptoms. We also administered steroid pulse therapy. Eyelid edema improved, and vision impairment improved 24 hours after the initiation of treatment. For severe cases with visual impairment, systemic administration of corticosteroids is recommended. In this case, administering steroid pulse therapy from an early stage resulted in improvement without sequelae. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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