[Baroreceptor reflex response to acute blood loss during induced hypotension--a comparison of sodium nitroprusside, prostaglandin E1 and trimethaphan]

Autor: C, Taneyama, H, Goto, K T, Benson, G K, Unruh, K, Arakawa
Rok vydání: 1990
Předmět:
Zdroj: Masui. The Japanese journal of anesthesiology. 39(5)
ISSN: 0021-4892
Popis: This experiment was designed to evaluate the reflexive heart rate (HR) response to acute blood loss during sodium nitroprusside (SNP), prostaglandin E1 (PGE1) and trimethaphan (TM) induced-hypotension in isoflurane anesthetized dogs. Reflexive increase in HR to acute blood loss was significantly greater during PGE1 induced-hypotension than during that with SNP. TM inhibited the reflexive HR response to acute blood loss. These results suggest that PGE1 induced-hypotension provides a safer margin than that with SNP and TM when rapid bleeding occurs during anesthesia and surgery.
Databáze: OpenAIRE