| Autor: |
L N, Jensen, L L, Christrup, L, Jacobsen, J, Bonde, H, Bundgaard |
| Rok vydání: |
1992 |
| Předmět: |
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| Zdroj: |
Acta pharmaceutica Nordica. 4(4) |
| ISSN: |
1100-1801 |
| Popis: |
The bioavailability of noscapine base administered in lozenges in a dose of 100 mg to twelve healthy volunteers, in a study using an open balanced cross-over design, was compared with that of 100 mg of noscapine hydrochloride given perorally as a mixture. The bioavailability of noscapine after administration in lozenges was significantly higher than that after administration of the drug as a mixture. It is concluded that the lozenges containing noscapine base may be a valuable alternative to the conventional noscapine hydrochloride mixture. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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