| Autor: |
Starzl, T. E., Marchioro, T. L., Peters, G. N., Kirkpatrick, C. H., Wilson, W. E. C., Porter, K. A., Rifkind, D., Ogden, D. A., Hitchcock, C. R., Waddell, W. R. |
| Jazyk: |
angličtina |
| Rok vydání: |
1964 |
| Předmět: |
|
| Popis: |
Six patients with terminal uremia due to glomerulonephritis or pyelonephritis were treated with heterografts from East African baboons. Immunosuppressive therapy was provided both before and after operation with azathioprine and prednisone and postoperatively local transplant irradiation and actinomycin C were administered intermittently. The individual rejection episodes in the post-transplant period could be reversed relatively easily but these reemred vigorously and repetitively, making it impossible to relax the stringent requirements of antirejectmion therapy. The continued need for high-dose immunosuppressive therapy precipitated lethal infections in the majority of cases. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
