Autor: |
Antonia, Angelopoulou, Dimitrios, Vlachakis, George P, Chrousos, Nikolaos, Cosmidis, Christos, Yapijakis |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Advances in experimental medicine and biology. 1339 |
ISSN: |
0065-2598 |
Popis: |
One of the most common genetic causes associated with thrombophilia is mutation G20210A of the coagulation factor II (F2) gene.Data collected from 355 unrelated Greeks examined for the mutation G20210A over a period of two decades were anonymously analyzed.The statistical analysis confirmed the importance of F2 G20210A in thrombosis and the significance of a positive family history of thrombosis. An interesting finding was the increased prevalence of G20210A in men with thrombotic events aged40 years.This study highlighted the great value of a positive family history of thrombosis and the importance of testing for this common mutation as a putative prevention strategy and a future biomarker for thrombophilia. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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