Analysis of novel domain-specific mutations in the zebrafish

Autor:	Ashley N, Turner, Reagan S, Andersen, Ivy E, Bookout, Lauren N, Brashear, James C, Davis, David M, Gahan, John P, Gotham, Baraa A, Hijaz, Ashish S, Kaushik, Jordan B, Mcgill, Victoria L, Miller, Zachariah P, Moseley, Cerissa L, Nowell, Riddhi K, Patel, Mia C, Rodgers, Yazen A, Shihab, Austin P, Walker, Sarah R, Glover, Samantha D, Foster, Anil K, Challa
Rok vydání:	2018
Předmět:	Models Molecular Binding Sites Embryo Nonmammalian Base Sequence Intracellular Signaling Peptides and Proteins Zebrafish Proteins Phenotype Protein Domains Ribonucleoproteins Holoprosencephaly Mutation Animals Amino Acid Sequence CRISPR-Cas Systems Zebrafish
Zdroj:	Journal of genetics. 97(5)
ISSN:	0973-7731
Popis:	Nodal-related protein (ndr2) is amember of the transforming growth factor type β superfamily of factors and is required for ventral midline patterning of the embryonic central nervous system in zebrafish. In humans, mutations in the gene encoding nodal cause holoprosencephaly and heterotaxy. Mutations in the
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::9bf5e2a2369f51902d41d48e350d19ee https://pubmed.ncbi.nlm.nih.gov/30555080 Zobrazit plný text záznamu Full text from SpringerLink