[The role of transcription factors in differentiation and development of the olfactory epithelium stem cells]

Autor: H, Xu, C Q, Liang, Y P, Xu, J P, Fan, J T, Lang
Rok vydání: 2018
Předmět:
Zdroj: Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery. 53(7)
ISSN: 1673-0860
Popis: As a sensor of the olfactory system, olfactory epithelium plays an important role in the olfactory system. In addition, olfactory epithelium is the only neuroepithelial epithelium in mammals that can maintain its self-renewal all along. There are of great significance in researching regenerating and repairing neural tissues, transplanting and treatment neural stem cells as well as the occurrence of olfactory disorders and intervention. This review will describe the characteristics of olfactory epithelial stem cells, and mainly summerize the function and significance of each transcription factor in the process of olfactory epithelial stem cell development and differentiation, in order to provide new ideas for the study of olfactory epithelial stem cells.嗅上皮既是嗅觉系统的感受器,又是哺乳动物体内唯一能够终生保持自我更新能力的神经性上皮,对神经组织的再生与修复、神经干细胞的移植与治疗、嗅觉障碍的发病与干预的研究都具有十分重要的意义。本文将阐述嗅上皮干细胞的特点,并针对各转录因子在嗅上皮干细胞发育和分化过程中发挥的功能和意义展开综述,以期为嗅上皮干细胞的研究提供新思路。.
Databáze: OpenAIRE