| Autor: |
A, Nanda, K, Al-Saeed, R, Dvorak, I, Al-Muzairai, H, Al-Sabah, M, Al-Arbash, Q A, Alsaleh |
| Rok vydání: |
2003 |
| Předmět: |
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| Zdroj: |
Clinical and experimental dermatology. 28(3) |
| ISSN: |
0307-6938 |
| Popis: |
Pemphigoid gestationis (PG) is a rare autoimmune disease of pregnancy. We report a series of 22 cases of PG in Kuwait. They constituted 18% of all the autoimmune bullous diseases registered in our centre over a span of 11 years. PG was observed to be the third most common bullous disease in our region. Ninety-five per cent of the patients were of Arab ethnicity. The clinical features observed in our patients were comparable to those reported elsewhere. Systemic steroids (prednisolone 20-60 mg daily) remained the mainstay of treatment to control the active disease and an optimal dose of 20 mg of prednisolone was maintained throughout the pregnancy and immediate postpartum period. We observed a favourable outcome of pregnancies complicated by PG without any associated maternal or foetal morbidity. Kuwaiti patients with PG were observed to have a predominance of HLA-DR3 and DQ2 antigens. No predominance of HLA-DR4 antigen was observed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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