| Autor: |
Hilda, Chávez-Navarro, Daniel Dimitri, Hernández-Cueto, Ariel, Vilchis-Estrada, David César, Bermúdez-Pulido, Gabriela, Antonio-Andrés, Rosendo, Luria-Pérez |
| Rok vydání: |
2014 |
| Zdroj: |
Boletin medico del Hospital Infantil de Mexico. 72(1) |
| ISSN: |
1665-1146 |
| Popis: |
Salmonella enterica, a species of facultative anaerobic bacteria, has demonstrated success as a live-attenuated bacterial vector for vaccination. S. enterica has also demonstrated promise as a therapeutic agent against cancer. Pre-clinical and clinical trials have shown that S. enterica is localized in both solid and semi-solid tumors as well as in metastatic tumors. Moreover, S. enterica reduces resistance to treatment with other agents. In this review we present the novel therapeutic anti-cancer approaches that use S. enterica both for its ability as a delivery system for heterologous moieties against cancer and for its direct anti-cancer properties. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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