Postnatal Exposure to Brief Hypoxia Alters Brain VEGF Expression and Capillary Density in Adult Mice

Autor: Michael B, Komarovsky, Constantinos P, Tsipis, Khalil A, Almotah, Walter F, Boron, Kui, Xu, Joseph, LaManna
Rok vydání: 2022
Předmět:
Zdroj: Advances in experimental medicine and biology. 1395
ISSN: 0065-2598
Popis: Perinatal hypoxia leads to changes in cerebral angiogenesis and persistent structural and functional changes in the adult brain. It may also result in greater vulnerability to subsequent challenges. We investigated the effect of postnatal day 2 (P2) hypoxic preconditioning on adult brain capillary density and brain vascular endothelial growth factor (VEGF) expression in mice. P2 mice were exposed to hypoxia (5% O
Databáze: OpenAIRE