[Clinical and morphologic features in patients with acute nephritis syndrome]

Autor: I, Mitić, D, Fele, P, Tepavcević, S, Djurić, P, Lenert, D, Bozić, S, Vodopivec, V, Sakac, T, Ilić, T, Djurdjević-Mirković, L, Sebić
Rok vydání: 1996
Předmět:
Zdroj: Srpski arhiv za celokupno lekarstvo. 124
ISSN: 0370-8179
Popis: Acute glomerulonephritis is a distinct clinical entity, more frequently found in younger age. We report 69 patients with AcGN (25 female and 44 male) mean age 26 years (range 15-58). The disease is clinically characterized with hypertension (57%), edema (59%) and oliguria (35%). Urine analysis showed microhaematuria/proteinuria (36%) and micro/macrohaematuria alone in 89%, while azothaemia was observed in 16% pts, and decreased serum complement levels in one third of patients, more often decrease of C3 (33%) than C4 (15%). Initial infection of the upper respiratory tract was seen in 65%, pneumonia in 8%. In 25% of pts. there were no data of previous infection. Cultures of pharyngeal smear revealed. Streptococcus only in 2 pts. Elevated AST titer was found in 32% pts. Eleven kidney biopsies were made, and histological examination showed 2 normal findings, 6 mesangioproliferative GH, 2 endocapillary GN and 1 membranoproliferative GN. Follow ups have showed urinary abnormalities in 25% of pts., without developing renal failure.
Databáze: OpenAIRE