Autor: |
C, Schewe, M, Rizzello, M, Dietel, S, Hauptmann |
Jazyk: |
němčina |
Rok vydání: |
2000 |
Předmět: |
|
Zdroj: |
Der Pathologe. 21(3) |
ISSN: |
0172-8113 |
Popis: |
PCR-based diagnosis of infectious diseases has developed into an important method in surgical pathology. We summarize our experience in this area based on 3500 analyses performed during the past 5 years. The peculiarity of material from a pathological laboratory is the risk of DNA fragmentation as a consequence of tissue fixation. For this reason the assays used must be adapted to this particular situation. PCR-based diagnosis of infectious diseases, if performed according to appropriate quality standards, is a safe and effective technique with high sensitivity and specificity and results in an etiologically based diagnosis. |
Databáze: |
OpenAIRE |
Externí odkaz: |
|