| Autor: |
T A, Danilova, N A, Borodiiuk, E A, Bazanova, O S, Grigor'eva, E N, Semenova, N Iu, Brineva, T K, Asoskova, V G, Nesterenko |
| Rok vydání: |
1999 |
| Předmět: |
|
| Zdroj: |
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (6) |
| ISSN: |
0372-9311 |
| Popis: |
A panel of monoclonal antibodies (McAb) to different determinants of group A Streptococcus polysaccharide (A-PS) has been studied. As revealed in this study, A-PS contains at least 4 determinants, common with different epidermal antigens. McAb, cross-reacting (CR) with different mammalian tissue antigens, have not been found to be group-specific. Experiments on the inhibition of the immunoenzyme reaction of McAb with A-PS indicate that CR determinants include rhamnose and beta-N-acetyl-D-glucosamine of rhamnose alone. In addition, we have confirmed our earlier suggestion that group-specific high-affinity precipitating antibodies acted on different sites of A-PS. Contrary to earlier opinions, antibodies to group-specific determinants of A-PS have been found not to react with epidermal antigens. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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