| Autor: |
J J, Jakubik, S M, Vicik, M M, Tannatt, B D, Kelley |
| Rok vydání: |
2004 |
| Předmět: |
|
| Zdroj: |
Haemophilia : the official journal of the World Federation of Hemophilia. 10(1) |
| ISSN: |
1351-8216 |
| Popis: |
West Nile Virus (WNV) was immediately and completely inactivated to below assay detection limits upon addition of solvent/detergent (S/D) to intermediate process pools of second and third generation B-domain deleted recombinant Factor VIII (BDDrFVIII; ReFacto, Wyeth, Cambridge, MA, USA). We verify that the S/D step provides robust enveloped virus inactivation (5 log(10)) and functions as a WNV barrier. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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