[The spatial organization of oligodendrocytes and pyramidal neurons in the frontal limbic cortex of patients with schizophrenia and healthy people: a computer morphometric study]

Autor:	V M, Vostrikov, O A, Artiukhova, M A, Kholmova, A V, Samorodov, N A, Uranova
Rok vydání:	2014
Předmět:	Oligodendroglia Case-Control Studies Pyramidal Cells Image Interpretation Computer-Assisted Limbic System Schizophrenia Humans Algorithms Frontal Lobe
Zdroj:	Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 113(12)
ISSN:	1997-7298
Popis:	To study the spatial organization of oligodendrocytes and pyramidal neurons in the frontal limbic cortex of patients with schizophrenia and healthy controls, the authors used a method of two-dimensional automated analysis of images. The decrease in the minimal distance between the oligodendrocyte and the nearest neuron by 20% and in the mean and maximal distances between neurons and the nearest oligodendrocytes by 10% and 9%, respectively, was found in the layer III in patients with schizophrenia. Therefore, this method allows to characterize the spatial organization of neurons and glia in the brain cortex not only in the normal brain but also in mental pathology.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::89d32bc56a386af95182574960b99838 https://pubmed.ncbi.nlm.nih.gov/24430038 Zobrazit plný text záznamu