The efficacy of atypical antipsychotics in the treatment of depressive symptoms, hostility, and suicidality in patients with schizophrenia
| Autor: | P E, Keck, S M, Strakowski, S L, McElroy |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Psychiatric Status Rating Scales
Clinical Trials as Topic Depressive Disorder Dibenzothiazepines Depression Pirenzepine Risperidone Piperazines Aggression Benzodiazepines Quetiapine Fumarate Suicide Thiazoles Treatment Outcome Hostility Olanzapine Schizophrenia Humans Multicenter Studies as Topic Schizophrenic Psychology Clozapine Antipsychotic Agents |
| Zdroj: | The Journal of clinical psychiatry. 61 |
| ISSN: | 0160-6689 |
| Popis: | Depressive symptoms and syndromal depression commonly occur in patients with schizophrenia. Schizophrenia is also associated with aggression directed at self and others. For this article, the available literature regarding the efficacy of clozapine, risperidone, olanzapine, quetiapine, and ziprasidone in the treatment of depression, hostility, and suicidality in patients with schizophrenia was reviewed. These studies suggest that atypical antipsychotics may exert therapeutic effects on depression and hostility as well as psychosis and that clozapine and olanzapine may reduce suicidality in patients with schizophrenia. These therapeutic actions appear to represent additional advantages of atypical antipsychotics compared with standard agents. |
| Databáze: | OpenAIRE |
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