| Autor: |
L, Yver, R, Maréchaud, D, Picaud, G, Touchard, A T, d'Eyzac, C, Matuchansky, D, Patte |
| Jazyk: |
francouzština |
| Rok vydání: |
1978 |
| Předmět: |
|
| Zdroj: |
La Nouvelle presse medicale. 7(18) |
| ISSN: |
0301-1518 |
| Popis: |
In a patient with occupational plumbism and a normal kidney function, EDTA therapy (1 g/24 h) resulted in a massive lead excretion (15 000 microgram/24 h) together with acute renal failure. A direct nephrotoxic effect of EDTA was excluded: after renal function returned to normal, EDTA could be subsequently readministered at progressively increasing doses (250 mg to 1 g/24 h) without any renal dysfunction. These findings strongly suggest a close relationship between the burden of lead mobilized by EDTA and the acute renal failure. This case can be classified as acute lead nephropathy of which only a few instances have been reported in the literature. The interest of monitoring lead excretion during chelation therapy is particularly emphasized. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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