| Autor: |
A P, Golikov, V A, Riabinin, P P, Golikov, B V, Davydov, V Iu, Polumiskov, D V, Rudnev, Z V, Taranova |
| Rok vydání: |
1996 |
| Předmět: |
|
| Zdroj: |
Terapevticheskii arkhiv. 68(1) |
| ISSN: |
0040-3660 |
| Popis: |
55 patients with unstable angina pectoris (group 1) received conventional treatment and neoton infusions (30 g/day for 3 days). Emoxipin was injected intramuscularly to 20 patients of group 2 (3 mg/kg for 20 days) and intravenously to 38 patients of group 3 (10 mg/kg). Control group consisted of 100 patients. Stabilization occurred in 89.2, 80 and 86.8% of group 1, 2 and 3 patients, respectively, versus 78% in controls. Holter ECG monitoring provided evidence on decline of myocardial ischemia for group 1 patients. Diene conjugates in group 1 decreased by 37%, ceruloplasmin level was higher by 30% compared to controls. Respective indices for emoxipin reached 52 and 37%, respectively. It is concluded that emoxipin and neoton produced a beneficial effect on unstable angina pectoris through correction of lipid peroxidation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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