| Autor: |
B, Chernow, R, Vigersky, J T, O'Brian, L P, Georges |
| Rok vydání: |
1982 |
| Předmět: |
|
| Zdroj: |
Journal of neurosurgery. 56(4) |
| ISSN: |
0022-3085 |
| Popis: |
A 38-year-old man developed secondary adrenal insufficiency as a consequence of intrathecal methylprednisolone administration. Evidence in support of this diagnosis included an absent plasma cortisol response to insulin-induced hypoglycemia, an inadequate adrenal response to exogenous corticotropin stimulation, a typical delayed response to prolonged corticotropin infusion over 3 days, and the findings of an elevated level of prednisolone in the cerebrospinal fluid a full 2 months after its administration. It is therefore recommended that patients receiving intrathecal steroids be carefully observed for the possible development of secondary adrenal insufficiency. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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